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Synthesis of a new class of tetronic acid derivatives: a one-pot three-component condensation reaction between isoquinoline or pyridine and dialkyl acetylenedicarboxylate with tetronic acid

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Abstract

Reaction of the zwitterions generated from isoquinoline or pyridine and dialkyl acetylenedicarboxylate with tetronic acid leads to 1,2-dihydroisoquinoline or 1,2-dihydropyridine tetronic acid derivatives without using any catalyst or activation at room temperature.

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Acknowledgments

We gratefully acknowledge financial support from the Research Council of Tehran University.

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Authors and Affiliations

  1. Department of Life Science Engineering, Faculty of New Science and Technology, University of Tehran, P.O. Box 14395-1561, Tehran, Iran

    Ali Hossein Rezayan & Hossein Sabahi

  2. Department of Chemistry, University of Isfahan, Isfahan, Iran

    Abbas Rahmati

  3. Department of Chemistry, Iran University of Science and Technology, Tehran, Iran

    Ali Maleki

  4. Sharif University of Technology, Tehran, Iran

    Somayyeh Kheirjou

Authors
  1. Ali Hossein Rezayan
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  2. Hossein Sabahi
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  3. Abbas Rahmati
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  4. Ali Maleki
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  5. Somayyeh Kheirjou
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Corresponding author

Correspondence to Ali Hossein Rezayan.

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Rezayan, A.H., Sabahi, H., Rahmati, A. et al. Synthesis of a new class of tetronic acid derivatives: a one-pot three-component condensation reaction between isoquinoline or pyridine and dialkyl acetylenedicarboxylate with tetronic acid. Monatsh Chem 144, 1051–1055 (2013). https://doi.org/10.1007/s00706-012-0919-x

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  • DOI: https://doi.org/10.1007/s00706-012-0919-x

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